CHEMOPREVENTION OF PROSTATE CANCER WITH FINASTERIDE

$79,525M01FY2000RRNIH

Weill Medical College Of Cornell Univ, New York NY

Investigators

Linked publications & trials

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Abstract

This is a multicenter NCI chemoprevention seven year clinical trial using finasteride to reduce the incidence of prostate cancer in healthy men. Finasteride is a 5-alpha-reductase inhibitor which may play a pivotal role in the initialization and progression of prostate cancer. After an initial run-in period, volunteers without evidence of prostate enlargement and with a normal PSA will be randomized to receive either daily finasteride or matched placebo for 7 years or until development of prostate-related symptoms.

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