INDINAVIR SULFATE W/ RITONAVIR IN HIV INFECTED PATIENTS

$0M01FY2000RRNIH

University Of North Carolina Chapel Hill, Chapel Hill NC

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Abstract

Indinavir has been shown in laboratory tests to have a strong effect on slowing the growth and spread of HIV-1. HIV-1 infection is thought to be the main cause of the acquired immunodeficiency syndrome (AIDS), which results in a gradual wearing down of the body's defenses against a variety of germs and other diseases. The main purpose of this study is to determine the safety and activity of indivavir in combination with ritonavir in HIV-infected patients who have failed protease inhibitor therapy.

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