BIOTRANSFORMATION PRODUCTS OF OXALIPLATIN COLORECTAL CANCER

$0M01FY2000RRNIH

University Of North Carolina Chapel Hill, Chapel Hill NC

Investigators

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Abstract

The purpose of this study is: 1) to evaluate the ratio of oxaliplatin to its biotransformation product following two separate infusions in patients with advanced colorectal cancer. 2) to determine the potential for the relative contribution of oxaliplatin and its biotransformation product to the development of neurotoxicity associated with oxaliplatin treatment.

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