GENETIC APPROACHES TO REGULATION OF LIPID METABOLISM

$469,110R37FY2003AINIH

University Of Illinois Urbana-Champaign, Champaign IL

Investigators

Linked publications & trials

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Abstract

This project is concerned with the molecular mechanisms that regulate membrane lipid synthesis and degradation in bacteria. The general approach is to use the approaches of chemistry, biochemistry, genetics, and molecular biology to understand the mechanisms of lipid metabolism and how these mechanisms are regulated. The mechanisms of fatty acid metabolism are highly conserved throughout biology and hence these studies may provide insight into the etiology of defective cellular membranes observed in many diseases.

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