OMAPATRILAT &LISINOPRIL IN TREATMENT OF MODERATE HYPERTENSION

$35,553M01FY2000RRNIH

University Of Southern California, Los Angeles CA

Investigators

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Abstract

The study will evaluate the effect of omapatrilat and lisinopril on blood pressure in subjects with salt-sensitive hypertension. a secondary objective is to compare the effects of the two drugs on urinary atrial natriuretic peptide (anp) on urinary cgmp and on plasma pra, anp, cgmp, angiotensin ii, angiotensin (1-7), endothelin and ace activity.

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