BRYOSTATIN IN COMBINATION W/ CISPLATIN IN CANCER PATIENTS

$0M01FY2000RRNIH

University Of Southern California, Los Angeles CA

Investigators

Linked publications & trials

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Abstract

This is a phase i consortium trial to establish the maximum tolerated dose of bryostatin-1 given as a 72 hour infusion followed by cis-platin bryostatin-1 will escalate but the cisplatin dose will be 50mg/m2. this study will evaluate the toxicities at each dose level along with the pharmacokinetics of cispaltin information obtained will be prelimary to guide further follow up studies with BRYOSTATIN-1.

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