INDINAVIR--EFFECT ON CARBOHYDRATE METABOLISM IN HIV PTS

$35,553M01FY2000RRNIH

University Of Southern California, Los Angeles CA

Investigators

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Abstract

The primary outcome variable will be insulin sensitivity, which will be calculated minimal model analysis of the IVGTT insulin and glucose data. Insulin sensitivity will be compared among baseline, 2 week and 8 week testing times by repeated measurs ANOVA. Secondary outcome measures will be first phase IVGTT insulin response, IVGTT incremental insulin area between 0-240 minute3s, and the OGTT glucose and insulin total areas (trapezoid method).

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