GENETIC RELATIONSHIPS BETWEEN NIDDM AND ATHEROSCLEROSIS IN HISPANICS

$35,553M01FY2000RRNIH

University Of Southern California, Los Angeles CA

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Abstract

Hispanics have a high prevalence of NIDDM. Surprisingly the risk of cardiovas-cular disease in Hispanic NIDDM is not as high as would be anticipated based upon studies in Caucasians and African-Americans. This study aims to test the hypothesis that 1) cardiovascular protective genes are prevalent in the Hispanic population and 2) a form of NIDDM which is not associated with cardiovascular disease is common in Hispanics and is genetically distinct from NIDDM that occurs in other ethnic groups.

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