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FEASIBILITY OF ORAL INSULIN THERAPY TO DELAY BETA CELL DESTRUCTION

$35,553M01FY2000RRNIH

University Of Southern California, Los Angeles CA

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Abstract

The hypothesis to be tested is that the daily ingestion of oral insulin into newly diagnosed children and adults with IDD will abrogate the autoimmune process (oral tolerance) underlying beta cell destruction either through insu-lin specific and/or islet cell antigen non-specific (bystander) immunological suppression and thus preserve endogenous insulin secretion.

View original record on NIH RePORTER →