TAXOL AND DOXIL IN PATIENTS WITH ADVANCED BREAST AND GYNECOLOGICAL MALIGNANCIES

$35,553M01FY2000RRNIH

University Of Southern California, Los Angeles CA

Investigators

Linked publications & trials

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Abstract

This study will try to determine the maximum tolerated dose combination of Doxil and Taxol in pts with advanced breast cancer and gynecological malig-nancies. Response rate and duration of response will be assessed in this patient population. In addition, the pharmacokinetics of Doxil plus Taxol when used together will be assessed and compared to known historical data. Treatment will consist of Taxol and Doxil given one day 1, with Taxol alone given on day 8. The cycle will be repeated every 28 days.

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