Thymidine &carboplatin chemotherapy for recurrent malignant glioma

$0M01FY2000RRNIH

University Of Michigan At Ann Arbor, Ann Arbor MI

Investigators

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Abstract

This is a phase II study for the treatment of recurrent malignant glioma with 24 hour infusions of thymidine to inhibit DNA damage repair enzymes to increase the cytotoxicity of carboplatin infused after hour 20 or thymidine.

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