WHOLE LIVER RADIATION DOSE ESCALATION TRIAL UTILIZING ETHYOL AMIFOSTINE

$206M01FY2000RRNIH

University Of Michigan At Ann Arbor, Ann Arbor MI

Investigators

Linked publications & trials

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Abstract

Although radiation has proven efficacy in the treatment of patients with cancers that started in or spread to the liver, its usefulness in the treatment of the whole liver is limited by the low total dose that can be safely tolerated. In this phase 1 study, Ethyol (amifostine) will be used in attempt to allow delivery of a higher total dose to the whole liver. This agent has been developed to selectively protect normal tissues against the toxicities of chemotherapy and radiation.

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