Trauma &organ failure--Role of local LPS binding protein

$0M01FY2000RRNIH

University Of Michigan At Ann Arbor, Ann Arbor MI

Investigators

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Abstract

We have demonstrated that lipopolysaccharide protein (LBP) is produced at extrahepatic sites. We are investigating whether this locally-produced LBP affects local immune responses to trauma and injury. As part of these studies, we will be cloning the promoter for the rat LBP gene and require DNA sequence analysis capabilities.

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