INTERACTION OF ASPIRIN W IBUPROFEN, ACETAMINOPHEN OR ROF

$0M01FY2000RRNIH

University Of Pennsylvania, Philadelphia PA

Investigators

Linked publications & trials

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Abstract

The primary objective of this Phase IV study is to determine whether administration of a non-selective cyclooxygenase (Cox) inhibitor (Ibuprofen), a non Cox inhibitor (Acetaminophen), or a selective Cox-2 (Rofecoxib) interferes with the irreversible antiplatelet effect of aspirin, as indicated by serum thromboxane levels (primary end-point).

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