ACTG374: STUDY 1) 141W94 &VX 478 PLUS 3TC PLUS ZDV OR 2) INDINAVIR +

$25,114M01FY2000RRNIH

University Of Pennsylvania, Philadelphia PA

Investigators

Linked publications & trials

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Abstract

The goals of t his study are two fold: 1) to determine the durability of successful virologic response to a 141W94/VX-478 containing regimen for at least 96 weeks post completion of a defined treatment course and 2) to determine if a four drug regimen including indinavir, a protease inhibitor with a presumably different resistance profile than 141W94/VX-478, plus nevirapine, 3TC and stavudine can salvage a failed or intolerant regimen that includes 141W94/ vx-478.

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