MECHANISMS OF HYPERTRIGLYCERIDEMIA IN HUMANS

$0M01FY2000RRNIH

University Of Washington, Seattle WA

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Abstract

The purpose of this study is to determine: 1) the mechanisms of primary hypertriglyceridemia related to VLDL overproduction and/or defective VLDL catabolism related to lipoprotein lipase or hepatic lipase; 2) the interaction of the above with secondary forms of hypertriglyceridemia; and 3) the response of LDL size, composition and mass to changes that occur in VLDL.

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