ACTG 400: PHASE 2 TRIAL OF SALVAGE ANTIRETROVIRAL THERAPIES FOR HIV INFECTION

$0M01FY2000RRNIH

Washington University, Saint Louis MO

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Abstract

Although current recommendations suggest that a combination of a protease inhibitor plus two nucleosides represents standard of care for HIV infection, as many as 50% of patients will relapse on such a regimen. This study will attempt to determine the best next treatment for patients who fail the most commonly used triple regimen, nelfinavir plus two nucleosides.

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