PHASE IV STUDY OF SAFETY OF PALIVIZUMAB (MEDI 493, SYNAGIS)

$0M01FY2000RRNIH

Washington University, Saint Louis MO

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Abstract

Respiratory illness from RSV infection can be life threatening for children with underlying lung disease or CHD. Palivizumab (MEDI-493, Synagis TM) is a humanized monoclonal IgG1 which has been shown to reduce the incidence of RSV-associated hospitalizations in children with underlying lung disease. A double-blind placebo-controlled, randomized multi-center study will be undertaken to assess the safety of palivizumab in children with CHD.

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