ORAL ZOLOLRESTAT IN NORMOTENSIVE, TYPE I DIABETICS WITH INCIPIENT NEPHROPATHY

$0M01FY2000RRNIH

Washington University, Saint Louis MO

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Abstract

Substantial clinical and experimental evidence now exists to suggest that increased flux of glucose through the ployol pathway may play and important role in the pathogenesis of the long-term complications of diabetes, particularly neuropathy, nephropathy, microvascular disease, and cataractogenesis.

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