GENETIC ANOMALIES OF C4, CR1 &FCYR JUVENILE IGA NEPHRITIS

$48,578M01FY2000RRNIH

Ohio State University, Columbus OH

Investigators

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Abstract

This study is testing the hypothesis that: 1) Abnormalities in complement and/or FcR mechanisms for processing and clearing circulating immune complexes (IC) are often present in IgA Nephritis (IgA-N), and 2) The extent of these abnormalities can determine whether the patient will experience juvenile or adult-onset IgA-N.

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