GEM 231 INFUSION IN PATIENTS WITH REFRACTORY SOLID TUMORS

$0M01FY2000RRNIH

University Of Alabama At Birmingham, Birmingham AL

Investigators

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Abstract

GEM 231 is a mixed backbone antisense obligodeoxynucleotide direct against the mRNA of protein Kinase A. The protein product is felt to be responsible for cell proliferation. This drug was administered as a 24 hour infusion once weekly X4 with a two week break.

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