ESTROGEN REPLACEMENT AND ATHEROSCLEROSIS (ERA) TRIAL

$0M01FY2000RRNIH

University Of Alabama At Birmingham, Birmingham AL

Investigators

Linked publications & trials

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Abstract

The purpose of ERA was to ascertain if the progression of coronary atherosclerosis can be modified by hormone replacement therapy in post-menopausal women with coronary artery disease. Subjects underwent coronary arteriography at baseline and were randomized to estrogen, estrogen plus progestin or placebo. After 3 years, coronary arteriograpy was repeated. The endpoint of the study is the change in coronary arterial narrowing from baseline to follow-up.

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