ONCONASE VS DOXORUBICIN IN MALIGNANT MESOTHELIOMA

$29,529M01FY2000RRNIH

University Of Alabama At Birmingham, Birmingham AL

Investigators

Linked publications & trials

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Abstract

This is a multicenter randomized comparative phase III trial of Onconase vs. Doxorubicin in patients with maglignant mesothelioma (Part I). This study was revised on February 16, 1999 to include a randomization between Doxorubicin vs. Onconase + Doxorubicin. Primary side effects of Onconase were myalgias, arthralgias, fatigue and mild legidema. Side effects of chemotherapy were myelosuppression, alopecia , mild nausea/vomiting and mucositis.

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