WOMENS ANGIOGRAPHIC VITAMIN &ESTROGEN (WAVE) TRIAL

$29,529M01FY2000RRNIH

University Of Alabama At Birmingham, Birmingham AL

Investigators

Linked publications & trials

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Abstract

The purpose of WAVE is to determine if female hormone replacement therapy (HRT) or antioxidant vitamins (c and E) will limit the progression of coronary artery disease (CAD) in post-menopausal women. This NHLBI-multicenter trial has randomized post-menopausal women with angiographicall documented CAD to HRT, vitamins, both or neither. After approximately 3 years follow-up, the subjects will undergo repeat coronary arteriography. The baseline and follow-up arteriograms will be compared to assess if the therapies were beneficial.

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