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WOMENS ISCHEMIC SYNDROME EVALUATION

$29,529M01FY2000RRNIH

University Of Alabama At Birmingham, Birmingham AL

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Abstract

WISE is an NHLBI-sponsored study to seek improved methods for identifying myocardial ischemia in women. Four clinical sites are using different technologies. At UAB, WISE testing consists of a combined persantine sestamibi radionuclide perfusion study and a gadolinium MRI perfusion study. All women have undergone diagnostic coronary arteriography for clinically-indicated reasons. Women with minimal or no significant epicardial coronary artery disease undergo P-31 metabolic assessment for microvascular ischemia. Other measurements include assessment of lipids, female hormones, Holter monitoring for ischemia, and long-term follow-up by telephone for clinical events.

View original record on NIH RePORTER →