ANTIMICROBIAL RESISTANCE (AMR) IN FUNGAL PATHOGENS OF AGRICULTURAL CROPS AND HUMANS IS EXPECTED TO INCREASE.BIORATIONAL FUNGICIDES HAVE BEEN SUGGESTED AS RESISTANCE MANAGEMENT TOOLS, BUT VERY LITTLE SCIENTIFIC EVIDENCE HAS BEEN PRESENT. USING PEACH AS A MODEL SYSTEM WE WILL DEVELOP NEW IPM TACTICS THAT INTEGRATE BIORATIONAL FUNGICIDES WITH CONVENTIONAL FUNGICIDES TO MANAGE BLOSSOM BLIGHT, GREEN FRUIT ROT, AND PREHARVEST BROWN ROT CAUSED BY MONILINIA FRUCTICOLA IN PEACH ORCHARDS. WE WILL REDUCE SELECTION OF AMR IN THE ENVIRONMENT BY REDUCING THEIR APPLICATION FREQUENCY AND DOSE RATE. WE WILL SUBSTITUTE AZOLES WITH A BIOLOGICAL CONTROL AGENT AT KEYTIMES DURING PEACH PRODUCTION AND STRATEGICALLY USE THEM AT LOWER DOSE RATES IN MIXTURES WHEN ABSOLUTELY NEEDED DURING PREHARVEST SEASON. RESULTS OBTAINED IN THIS SEED GRANT WILL BE USED IN A FOLLOW UP GRANT TO REDUCE OR ELIMINATE SELECTION FOR AZOLE RESISTANCE IN NON-TARGET (E.G. ASPERGILLUS FUMIGATUS AND CANDIDA SPP.) AND TARGET (E.G. M. FRUCTICOLA) ORGANISMS IN EASTERN STONE FRUIT ORCHARDS.