** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** WE AIM TO DEVELOP NOVEL TOOLS FOR INTEGRATED WEED MANAGEMENT STRATEGIES FOR COTTON, TARGETING THE MOST PROBLEMATIC AND/OR MOST COMMON WEED SPECIES. THESE TOOLS WILL SUPPLEMENT COVER CROPS, IMPROVE THE EFFICACY OF HERBICIDES, AND PROVIDE ANOTHER NON-CHEMICAL TOOL FOR WEED MANAGEMENT THAT COULD REDUCE WEED SEEDBANK AND CURB HERBICIDE-RESISTANT WEED EVOLUTION. THE OBJECTIVES ARE TO: 1) EVALUATE THE EFFECT OF TRINEXAPAC-ETHYL (TE) ON HERBICIDE ACTIVITY, WEED FECUNDITY AND GERMINATION; 2) EXTEND THE RESIDUAL ACTIVITY OF HERBICIDES USING SOIL ADJUVANTS; 3) DEFINE MICROWAVE SPECIFIC ENERGIES CAPABLE OF INACTIVATING WEED SEEDS IN SOIL WHILE MAINTAINING SOIL HEALTH IN TERMS OF FERTILITY AND BENEFICIAL MICROBES. MICROWAVE APPLICATION HAS NOT BEEN EXHAUSTIVELY EXPLORED FOR WEED MANAGEMENT BEFORE. PRELIMINARY DATA SHOW SOME EXCELLENT COBINATIONS OF TE X HERBICIDE TO MANAGE PALMER AMARANTH AND COMMON LAMBSQUARTERS. WE WILL TEST TWO DOSES OF TE AND SEVEN HERBICIDES ON FOUR BROADLEAF SPECIES AND SIX HERBICIDES ON FOUR GRASS SPECIES. TWO SOIL ADJUVANTS AND 12 SOIL-APPLIED HERBICIDES WILL BE TESTED IN TWO SOIL TYPES. OUR PRELIMINARYTESTS SHOWED THAT MICROWAVE APPLICATION CAN KILL WEEDY RICE SEEDS UP TO 6 CM SOIL DEPTH. MICROWAVE APPLICATION DID NOT AFFECT THE SOIL NUTRIENT PROFILE NOR THE MICROBIAL POPULATION. WE WILL TEST MICROWAVE EFFICACY ON TEN KEY WEEDS, REPRESENTING A WIDE RANGE OF SEED TYPES. THIS PROPOSAL IS SUBMITTED TO THE COMMODITY BOARD TOPIC A1811: DEVELOP ADVANCED INTEGRATED PEST MANAGEMENT (IPM) TECHNOLOGIES AND/OR TECHNIQUES THAT WILL COMPLEMENT AND PRESERVE CURRENT CROP PROTECTION TECHNOLOGIES/PRODUCTS FOR WEEDS IN COTTON, WHILE SIMULTANEOUSLY REDUCING THE RELIANCE ON CONVENTIONAL PESTICIDES.