** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** TWO SPECIES OF CATTLE FEVER TICKS ARE THE ONLY ARTHROPODS IN NORTH AMERICA THAT CAN TRANSMIT THE PATHOGENS THAT CAUSE THE HIGHLY FATAL DISEASE OF CATTLE KNOWN AS BOVINE BABESIOSIS OR TEXAS CATTLE FEVER. IN THE ABSENCE OF DRUGS OR VACCINES TO PROTECT CATTLE FROM THIS DISEASE, THE BEST DISEASE CONTROL IS TO PREVENT THE TICK VECTORS FROM BECOMING RE-ESTABLISHED IN THE US FROM MEXICO WHERE BOTH THE TICKS AND DISEASE PATHOGENS REMAIN ENDEMIC. AT RISK ARE US CATTLE THAT ARE IMMUNOLOGICALLY SUSCEPTIBLE TO INFECTION THROUGH TICK BITE OF CATTLE FEVER TICKS.THE RISKS OFINCURSIONS, ESTABLISHMENT AND OUTBREAKS OF CATTLE FEVER TICKS IN THE US ARE ASSOCIATED WITH TICK-HOST-HABITAT-CLIMATE INTERACTIONS. EACH TYPE OF INTERACTION HAS BEEN EXTENSIVELY STUDIED BY SCIENTISTS AND SPECIALISTS OF THE STATE AND FEDERAL REGULATORY PROGRAMS THAT OVERSEE THE US CATTLE FEVER TICK ERADICATION PROGRAM. DIFFERENT DATASETS AND OPERATIONAL SUBPROGRAMS HAVE BEEN DEVELOPEDALONG THE LINES OF EACH TYPE OF INTERACTION FOR USE IN DETECTING, CONTAINING AND ELIMINATING CATTLE FEVER TICKS. THE OBJECTIVESOF THIS PROJECT ARE TO ASSIMILATE THE DIFFERENT DATASETS INTO AN INTERACTIVE COMPUTER-BASED PLATFORM THAT PERMITS THE EXAMINATION, ANALYSIS, AND INTERPRETATION OF FACTORS INFLUENCING CATTLE FEVER TICKS, WITH THE GOAL OF DEVELOPING A TOOL TO IDENTIFY EVERCHANGINGRISKS AND HOW TO BEST PREVENT AND/OR MITIGATE CATTLE FEVER TICK INFESTATIONS.