AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION. TRITRICHOMONAS IS A SEXUALLY TRANSMITTED PARASITE OF CATTLE THAT CAUSES EMBRYONIC DEATH LOSS. IN THIS PROJECT, WE ARE WORKING TOWARD IMPROVED DIAGNOSTIC TESTING AND VACCINES FOR THIS PARASITE. WE WILL BE ANALYZING THE GENES TRANSCRIBED BY THE PARASITED AND RECOGNIZED BY THE IMMUNE SYSTEM. NEXT, WE WILL DETERMINE IF INFECTED CATTLE HAVE A UNIFORM ANTIBODY RESPONSE AGAINST THE PARASITE. FINALLY, WE WILL TEST DISCOVERED IMMUNOGENIC PEPTIDES AS POSSIBLE VACCINE CANDIDATES IN A CHALLENGE STUDY.

$790,000FY2022National Institute of Food and AgricultureUSDA

Iowa State University Of Science And Technology

Investigators

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**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** TRITRICHOMONAS IS A SEXUALLY TRANSMITTED PARASITE OF CATTLE THAT CAUSES EMBRYONIC DEATH LOSS. IN THIS PROJECT, WE ARE WORKING TOWARD IMPROVED DIAGNOSTIC TESTING AND VACCINES FOR THIS PARASITE. WE WILL BE ANALYZING THE GENES TRANSCRIBED BY THE PARASITED AND RECOGNIZED BY THE IMMUNE SYSTEM. NEXT, WE WILL DETERMINE IF INFECTED CATTLE HAVE A UNIFORM ANTIBODY RESPONSE AGAINST THE PARASITE. FINALLY, WE WILL TEST DISCOVERED IMMUNOGENIC PEPTIDES AS POSSIBLE VACCINE CANDIDATES IN A CHALLENGE STUDY. · GrantIndex