**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** UNMANNED AERIAL APPLICATION SYSTEMS (UAASS) ARE DEVELOPING INTO A PRACTICAL TECHNOLOGY FOR LIQUID AND DRY MATERIAL APPLICATIONS. THEY FILL THE GAP IN AREAS THAT GROUND SPRAYING RIGS AND LARGE MANNED AERIAL APPLICATORS CANNOT EASILY ACCESS OR DO NOT HAVE A COMPETITIVE ECONOMIC GAIN. HOWEVER, DESPITE A COMPREHENSIVE RESEARCH FOUNDATION ON SPRAYING AND SITE-SPECIFIC TECHNOLOGIES, EXTENSIVE STUDIES IN THE AREA OF UNMANNED AIRCRAFT SYSTEM BASED SENSING, AND PILOT STUDIES IN UAAS SPRAYING PATTERN CHARACTERIZATION, LITTLE PROGRESS HAS BEEN MADE IN STUDYING SOLUTIONS FOR SITE-SPECIFIC APPLICATIONS USING UAASS; AN AREA IN WHICH THE TECHNOLOGY HOLDS ITS TRUE VALUE.THE GOAL OF THE PROPOSED PROJECT IS TO DEVELOP AN INTELLIGENT AND SCALABLE UNMANNED AERIAL APPLICATION SOLUTION FOR SITE-SPECIFIC WEED MANAGEMENT. SPECIFIC OBJECTIVES ARE: (1) DEVISE A REAL-TIME EDGE-COMPUTING COMPONENT FOR SENSING AND DECISION-MAKING ONBOARD AN UNMANNED AIRCRAFT SYSTEM THAT MAPS THE SPATIAL PATTERN OF WEED PRESSURE AND GENERATES ROUGH PRESCRIPTION MAPS FOR TIME-SENSITIVE APPLICATIONS; (2) DEVELOP A CLOUD-COMPUTING COMPONENT FOR DATA STORAGE THAT FACILITATES DERIVING MORE ACCURATE PRESCRIPTION MAPS AND LONG-TERM, USER-CONTRIBUTED REFINEMENT OF THE DECISION-MAKING MODEL; AND (3) CUSTOMIZE AND TEST A PROTOTYPE OF A SITE-SPECIFIC UAAS THAT IMPLEMENTS FLIGHT AND APPLICATION PLANS DERIVED FROM THE PRESCRIPTION MAP.WE EXPECT THAT THIS STUDY WILL PROVIDE A SOLID FRAMEWORK FOR INTELLIGENT SITE-SPECIFIC UAAS TECHNOLOGIES. THIS WORK ALSO AIMS TO STIMULATE AND ADVANCE FURTHER RESEARCH AND DEVELOPMENT IN THE AREA THROUGH ITS INNOVATIONS, CONTRIBUTE TO A MORE ECONOMICALLY AND ENVIRONMENTALLY SUSTAINABLE AGROECOSYSTEM, AND KEEP THE UNITED STATES AT THE FOREFRONT OF PRECISION AGRICULTURAL TECHNOLOGY.