PIGS EXPERIENCE NUMEROUS STRESSORS THROUGHOUT THEIR LIFE, INCLUDING THE PRENATAL AND EARLY POSTNATAL PERIODS. THESE TWO PERIODS IN THE PIGLETS' LIFE ARE ESSENTIAL TO DEFINING HOW THE WILL RESPONDS TO THEIR ENVIRONMENT THROUGHOUT LIFE. UNFORTUNATELY, MANAGEMENT PRACTICES FOCUS ON THE YOUNG PIGLET ITSELF IN AN ATTEMPT TO IMPROVE SURVIVAL, HEALTH, AND PRODUCTIVITY, WHILE IGNORING THE PRENATAL AND EARLY POSTNATAL EXPERIENCES. THE STRESSTHE SOW EXPERIENCES DURING PREGNANCY CAN AFFECT THE PHYSIOLOGY AND BEHAVIOR OF PROGENY BEFORE AND AFTER BIRTH, THEREFORE ATTEMPTS TO IMPROVE THE SURVIVABILITY, HEALTH, PERFORMANCE, AND OVERALL WELL-BEING OF PIGS MUST BEGIN WITH THE PREGNANT SOW. LIMITED INFORMATION EXISTS ON THE LONG-TERM IMPACTS OF STRESS ON THE HEALTH, BEHAVIOR, AND WELL-BEING OF HER PROGENY. THEREFORE, THE OVERALL OBJECTIVE IS TO CHARACTERIZE THE DIFFERENTIAL BEHAVIORAL AND IMMUNOLOGICAL PROFILES AND WELFARE CONSEQUENCE ON THE PROGENY FROM SOWS SUBJECTED TO STRESS AT EARLY, MIDDLE, AND LATE GESTATION THAT ARE INDICATIVE OF WELFARE STATUS. THESE RESULTS WILL ENHANCE OUR UNDERSTANDING OF THE IMPACT STRESS DURING PREGNANCY HAS ON THE WELL-BEING OF THE OFFSPRING IN THE SHORT- AND LONG-TERM. THESE RESULTS WILL MAKE IT POSSIBLE TO DEVELOP METHODOLOGIES FOR THE SELECTION OF ANIMALS WITH IMPROVED WELFARE AND DEVELOP MANAGEMENT STRATEGIES FOR MITIGATING ADVERSE EFFECTS OF STRESS ON BOTH THE SOW AND HER PROGENY.