PORCINE RESPIRATORY DISEASE POSES A MAJOR CHALLENGE TO BOTH VETERINARIANS AND PORK PRODUCERS. CONVENTIONAL METHODS FOR IDENTIFICATION OF PATHOGENS CAUSING PORCINE RESPIRATORY DISEASE ARE TIME CONSUMING AND REQUIRE SPECIALIZED LABORATORY FACILITIES. IT ALSO INVOLVES MULTIPLE TESTS TO DETECT DIFFERENT PATHOGENS. MPS TECHNOLOGY, PROPOSED IN THIS PROJECT, CAN BE USED TO DEVELOP AN ACCURATE, AFFORDABLE, FAST AND EASY-TO-USE TEST FOR PATHOGEN DETECTION, INCLUDING SIMULTANEOUS DETECTION OF MULTIPLE PATHOGENS IN A SINGLE TEST. USING THE MPS PLATFORM AS A PORTABLE IN-FARM TESTING KIT, WOULD BRING INFECTIOUS DISEASE DIAGNOSIS IN SWINE PRODUCTION SYSTEMS TO A NEW LEVEL. AT THE SUCCESSFUL COMPLETION OF THIS PROJECT, WE WOULD HAVE AN MPS SYSTEM THAT WILL ENABLE EARLY RAPID DETECTION OF TWO COMMON PORCINE RESPIRATORY PATHOGENS, ALLOWING IMPLEMENTATION OF QUICK AND EFFECTIVE PREVENTION, AND CONTROL STRATEGIES FOR THESE RESPIRATORY INFECTIONS IN SWINE. ONE COULD ALSO ENVISION THE POTENTIAL FOR EXTENDING THIS TECHNOLOGY TO OTHER SWINE DISEASES, AND TO INFECTIONS IN OTHER ANIMAL SPECIES. THE PORTABILITY OF THIS DETECTION DEVICE COUPLED WITH A SMARTPHONE INTERFACE WILL ALLOW TESTING IN REMOTE AREAS AND UNDER FIELD SETTINGS, SUCH AS IN A FARM OR A PRODUCTION SYSTEM. BY TRANSMITTING TEST RESULTS COLLECTED FROM DISTANT LOCATIONS TO CENTRALLY LOCATED DATA ANALYSIS UNITS, VETERINARIANS LOCATED AWAY FROM FARMS CAN HAVE REAL-TIME EPIDEMIOLOGICAL DATA AT THEIR FINGERTIPS. THIS WOULD ALSO SIGNIFICANTLY REDUCE THE COSTS FOR MONITORING INFECTIONS AT THE REGIONAL LEVEL. THESE POSSIBILITIES WOULD ALTER CURRENT PARADIGMS FOR DISEASE SURVEILLANCE AND ENHANCE THE ABILITY TO EVALUATE AND MONITOR DISEASE CONTROL PROTOCOLS IN REAL-TIME.