**AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** STRINGENT ENVIRONMENTAL REGULATIONS AND POPULATION GROWTH ARE NECESSITATING A SIGNIFICANT INCREASE IN CROP PRODUCTION WHILE MINIMIZING APPLIED NITROGEN (N) FERTILIZER REACTIVE LOSS IN THE ENVIRONMENT. THIS WORK WILL SYNTHESIZE MULTIFUNCTIONAL N-EFFICIENT IONIC UREA AND AMMONIUM CARBONATE CO-CRYSTALS USING GREEN MECHANOCHEMICAL METHODS BASED ON ABUNDANT MINERALS AND INORGANIC SALTS TO ACHIEVE A SYMBIOTIC RELATIONSHIP BETWEEN N FERTILIZER USE AND FARMING USING MINERALS AS A NUTRIENT SOURCE. IN PARTICULAR, THE PROPOSED WORK WILL SYNTHESIZE UREA AND AMMONIUM CARBONATE COCRYSTALS USING MACRONUTRIENT MG- AND CA-SALTS, SUCH AS THE CORRESPONDING CHLORIDES, NITRATES, SULFATES AND PHOSPHATES. IT WILL FURTHER SYNTHESIZE COCRYSTALS OF MICRONUTRIENT CU AND ZN WITH UREA USING CHLORIDE, NITRATE, SULFATE AND PHOSPHATE CU AND ZN SALTS AS WELL AS CU AND ZN-BEARING MINERALS. IT WILL UTILIZE MECHANOCHEMISTRY TO OBTAIN SOLUBLE POTASSIUM (K) FROM INSOLUBLE K-BEARING MINERALS. FINALLY, IT WILL SYNTHESIZE UREA COCRYSTALS WITH ABUNDANT DRYWALL GYPSUM WASTE. NH3 EMISSION PROPERTIES WILL BE TESTED IN THE LAB WHILE SUITABILITY OF THESE COCRYSTALS AS FERTILIZER MATERIALS WILL BE TESTED FOR N-EFFICIENCY FOLLOWED BY THE GREENHOUSE EXPERIMENTS. THE ULTIMATE GOAL IS TO REDUCE NITROGEN GAS LOSS FROM THE NON-POINT SOURCES (AGRICULTURAL FIELDS) INTO THE AIR AND WATERSHED WHILE ALSO AVOIDING THE USE OF SYNTHETIC ORGANOPHOSPHORUS COMPOUNDS CURRENTLY USED TO INHIBIT SOIL ENZYMES. THE SOCIETAL BENEFITS REALIZED WILL BE (A) REDUCING NUTRIENT RUNOFF FROM AGRICULTURAL NONPOINT SOURCES THUS (B) DECREASING ENERGY REQUIREMENTS NEEDED FOR TREATMENT OF SUCH WASTEWATER AND CONSEQUENTIALLY (C) SIGNIFICANTLY IMPROVING AND SIMPLIFYING MANAGEMENT PRACTICES OF NONPOINT SOURCES WITH UP TO 30% MORE NUTRIENTS BECOMING MORE AVAILABLE TO THE CROPS.