ALTHOUGH THERE IS A GROWING LITERATURE ON THE USE OF NANOTECHNOLOGY IN FOOD PRODUCTION, THE VAST MAJORITY OF THIS WORK HAS FOCUSED ON METAL-BASED NANOPARTICLES. ALTHOUGH SOME BENEFIT HAS BEEN DEMONSTRATED, METAL-BASED NANOPARTICLES CAN ACCUMULATE IN SOIL AND CONTAMINATE THE ENVIRONMENT. THEREFORE, THERE IS A CRITICAL NEED FOR SAFER AND MORE SUSTAINABLE NANOMATERIALS FOR AGRICULTURAL USE. WE HAVE PRELIMINARY DATA DEMONSTRATING THE POTENTIAL OF NANOSCALE SULFUR AS A MULTI-FUNCTIONAL SUSTAINABLE AGRICULTURAL AMENDMENT TO PROMOTE FOOD PRODUCTION AND SAFETY. SINCE SULFUR IS A CRITICAL ELEMENT FOR PLANT GROWTH, WE HYPOTHESIZE THAT NANOSCALE SULFUR APPLICATION WILL IMPROVE PLANT GROWTH AND PRODUCTIVITY, CONTROL DISEASE, AND PREVENT HEAVY METAL ACCUMULATION BY FOOD CROPS. THE LONG-TERM GOAL OF THIS PROJECT IS TO DEVELOP A SAFER AND MORE SUSTAINABLE SULFUR-BASED PLATFORM FOR PREVENTING TOXIC METALS ACCUMULATION IN FOOD CROPS AND AS NOVEL NANOSCALE PESTICIDE FOR FOOD PRODUCTION, BOTH IN FIELD AND URBAN AGRICULTURE SCENARIOS. THIS WORK WILL SIGNIFICANTLY ADVANCE THE FIELD OF NANO-ENABLED AGRICULTURE AND SERVE AS AN IMPORTANT PLATFORM TO COMBAT GLOBAL FOOD INSECURITY.