THE ELDERLY SUFFER MANY AGE RELATED DYSFUNCTIONS AND DISEASES. CURRENT THINKING INDICATES THAT A LARGE PROPORTION OF THESE CONDITIONS CAN BE AVOIDED BY LEADING HEALTHIER LIFESTYLES EARLIER IN LIFE. A MAJOR INFLUENCE IN LIFESTYLES IF THE FOOD WE EAT. AS WAS SAID BY HIPPOCRATES 2500 YEARS AGO FOOD IS MEDICINE. BY COMPLETING THIS COMPREHENSIVE, SYSTEMATIC STUDY, WE WILL DEMONSTRATE FOR THE FIRST TIME HOW CONSUMING DIETS WITH CARBOHYDRATES WHICH BREAK DOWN DIFFERENTLY MAY HAVE AN EFFECT ON INFLAMMATION, INTEGRITY AND FUNCTION OF THE RETINA AS WE AGE, THE BODY'S ABILITY TO DEFEND ITSELF FROM DAMAGE CAUSED BY FREE RADICALS, THE BODY'S COLLECTION OF METABOLITES, AND THE BODY'S COLLECTION OF MICRO-ORGANISMS. THE STUDY WILL ALSO SHOW INTERACTIONS BETWEEN THESE FACTORS. THIS INTEGRATED BIOLOGICAL MECHANISM WILL MARKEDLY STRENGTHEN OUR CAPACITY TO RECOMMEND CARBOHYDRATE-HEALTHIER DIETS THAT WILL REDUCE RISK FOR AMD, AND POSSIBLY THE MANY OTHER AGE-RELATED CONDITIONS THAT ARE ASSOCIATED WITH CONSUMING TYPICAL AMERICAN HIGHER GLYCEMIA DIETS SUCH AS HEART DISEASE AND DIABETES. THIS COULD PROVIDE AN APPROACH TO EXTENDING HEALTHIER LIVES FOR MILLIONS OF PEOPLE THAT DEMANDS VERY LITTLE TECHNOLOGY.