LONG-DURATION SPACEFLIGHT IS CHALLENGING FOR THE MANY BODY PARTS THAT HELP US MAINTAIN NORMAL MOVEMENTS AND PERFORM WELL WHICH INCLUDE OUR BONES JOINTS VISION AND BRAIN. ASTRONAUTS MUST PERFORM TO THE BEST OF THEIR ABILITIES WHEN THEY ARE TRAVELING TO A DESTINATION LIKE THE MOON OR MARS AND WHEN THEY REACH THE DESTINATION. DURING THE TRAVEL TO THE DESTINATION OR ON THE SURFACE OF THE PLANET/MOON ASTRONAUTS COULD FACE DANGEROUS SITUATIONS THAT REQUIRE RAPID ESCAPE MOVEMENTS OR SITUATIONS WHERE THE BODY COULD BE IN PERIL DUE TO SURROUNDINGS (LIKE WHEN CLIMBING THE ROUGH TERRAIN OF A MOUNTAIN OR INTO A VALLEY). IF AN ASTRONAUT IS NOT PERFORMING WELL DUE TO ALTERED VISUAL PERFORMANCE BUT ALSO HAS DAMAGED BONES DUE TO LOW GRAVITY OR RADIATION THE ASTRONAUT COULD BE AT RISK OF CATASTROPHIC JOINT TEARS OR BONE BREAKS WHILE EXPLORING UNEVEN/DANGEROUS TERRAINS OR DURING A REQUIRED RAPID ESCAPE INTO OR OUT OF A SPACECRAFT. OUR LABORATORY HAS MEASURED THAT PERFORMANCE IS ALTERED IN RODENTS AFTER ~35 DAYS IN ORBIT ON THE INTERNATIONAL SPACE STATION. HOWEVER THESE MEASUREMENTS WERE TAKEN ON A TREADMILL MOVING FORWARD AT A CONSTANT SPEED. THIS DOES NOT REPRESENT THE DANGEROUS TERRAIN OF THE MOON OR MARS OR OTHER RAPID MOVEMENTS ASTRONAUTS WOULD FACE DURING SPACEFLIGHT. THUS OUR INTENT IS TO DEVELOP AND FABRICATE A METHOD TO BETTER REFLECT LOCOMOTOR PERFORMANCE IN RODENT MODELS OVER UNEVEN AND DANGEROUS LUNAR/ MARTIAN SURFACES IN ORDER TO BEST ASSESS HOW COMBINED SPACEFLIGHT HAZARDS (E.G MICROGRAVITY AND RADIATION) CAUSE DEFICITS IN ASTRONAUT PERFORMANCE MEASURE TIME TO RECOVERY AND IDENTIFY COUNTERMEASURES. WE WILL CREATE A PLATFORM ON WHICH SITS OUR TREADMILL THAT CAN MEASURE MOUSE AND RAT PERFORMANCE. HOWEVER THE PLATFORM CAN MOVE (ONE MOVABLE PORTION UNDER EACH CORNER SUPPORT OF THE TREADMILL) IN A MANNER THAT CAN REFLECT UNEVEN TERRAIN OR A RAPID ESCAPE MOTION. THEN WE CAN MEASURE HOW THE ANIMALS THAT HAVE PREVIOUS BEEN EXPOSED TO SPACEFLIGHT CONDITIONS (LIKE REDUCED GRAVITY OR RADIATION) RESPOND. THIS PLATFORM AND PERFORMANCE MEASUREMENT DEVICE CAN THEN BE USED TO TEST WAYS TO MAXIMIZE PERFORMANCE AND THUS IMPROVE THE TECHNOLOGIES AND APPROACHES USED DURING SUCCESSFUL MANNED SPACE EXPLORATION.