THE COVID-19 PANDEMIC STARTED IN JANUARY 2020 AT WUHAN THE CAPITAL OF HUBEI PROVINCE LOCATED IN CENTRAL CHINA HAS BEEN RAPIDLY EVOLVING AND CAUSED UNFORESEEN AND UNPRECEDENTED DISTURBANCE TO BOTH THE HUMAN SOCIETIES AND THE EARTH SYSTEM. TO SLOW DOWN THE SPREAD OF THIS PANDEMIC DRASTIC MEASURES HAVE BEEN TAKEN WORLDWIDE WHICH HAVE SIGNIFICANTLY REDUCED EMISSIONS IN MANY KEY SOURCE REGIONS AND ARE MAKING RAPID AND POTENTIALLY LONG-LASTING IMPACT TO ATMOSPHERIC CHEMISTRY. THE PROPOSED RESEARCH WILL CONSIST OF (1) CONSTRAINING THE ATMOSPHERIC DISPERSION PATTERNS FOR THREE AIR BASINS (PO VALLEY IN ITALY JIANGHAN PLAIN IN CHINA AND SOUTH COAST AIR BASIN IN USA) USING A LONG-LIFETIME SPECIES CO OBSERVED BY TROPOMI (2) ESTIMATING EMISSION AND LIFETIME OF NOX THAT IS CO-EMITTED WITH CO AT AIR BASIN SCALES USING BOTH TROPOMI AND OMI OBSERVATIONS AND (3) APPLYING TIME SERIES ANALYSIS ON THE DERIVED NOX EMISSION AND LIFETIME DATA FROM 2004 TO 2021. THE PROPOSED RESEARCH DIRECTLY RESPONDS TO THE NASA RAPID RESPONSE AND NOVEL RESEARCH IN EARTH SCIENCE (RRNES) SOLICITATION (A.28) BY MAKING QUANTITATIVE CONNECTIONS BETWEEN CHANGES IN ANTHROPOGENIC FORCINGS E.G. EMISSIONS AND THE RELATED EARTH SYSTEM ENVIRONMENTAL RESPONSE TO THE COVID-19 PANDEMIC. BY COMBINING HIGH-RESOLUTION TROPOMI DATA WITH LONG-TERM RECORD FROM OMI WE ARE ADDRESSING CURRENT CHANGES AS PART OF REGIONAL OR GLOBAL BUDGETS.