THE ABILITY TO MANUFACTURE USEFUL COMPONENTS IN SPACE HAS THE POTENTIAL TO PROVIDE SIGNIFICANT BENEFITS TO THE AEROSPACE INDUSTRY AND EVENTUALLY ENABLE TRULY EARTH-INDEPENDENT EXPLORATION. A SYSTEM THAT INCORPORATES IN-SITU MANUFACTURING CAPABILITY CAN CREATE COMPONENTS IN ORBIT EITHER FROM RAW MATERIALS THAT ARE LAUNCHED FROM EARTH OR EXTRATERRESTRIAL MATERIALS BREAKING THE CURRENT SPACE SUPPLY PARADIGM. IN-SPACE MANUFACTURING IS A CROSS-CUTTING APPLICATION PROVIDING BENEFITS ACROSS DIFFERENT SUBSYSTEMS SPACECRAFT AND SYSTEM ARCHITECTURES. ON-ORBIT MANUFACTURING CAPABILITY HAS THE POTENTIAL TO BE A VERY PROFITABLE ENTERPRISE SINCE IN EFFECT IT ACCOMPLISHES THE SAME FUNCTION AS THE GLOBAL LAUNCH INDUSTRY PROVIDING USEFUL ELEMENTS ON ORBIT WHERE OTHERS CAN BENEFIT FROM THEM. CUSTOMER SYSTEMS SUCH AS THE ISS FUTURE STATIONS SATELLITES AND DEEP SPACE EXPLORATION MISSIONS MAY RECEIVE MANUFACTURING SUPPORT THROUGH DEDICATED EMBEDDED EQUIPMENT OR FREE-FLIER FACILITIES. SPACE-BASED MANUFACTURING WILL BE AN IMPORTANT ASPECT OF THE NEW SPACE ECONOMY ENABLED BY TECHNOLOGY AND DRIVEN BY A ROBUST TWO-SIDED MARKET SYSTEM. ADDITIVE MANUFACTURING METHODS ARE WELL SUITED FOR SPACE-BASED APPLICATIONS DUE TO THEIR UNIQUE CAPABILITIES INCLUDING EFFICIENT RESOURCE USAGE LOW VOLUME FORM FACTOR AND BROAD RANGE OF AVAILABLE MATERIALS. 3-D PRINTING ALSO ENABLES COMPONENT GEOMETRIES AND HETEROGENEOUS MATERIALS THAT HAVE BEEN HERETOFORE IMPOSSIBLE WITH TRADITIONAL PRODUCTION METHODS. THESE METHODS ARE ALSO COMPATIBLE WITH IN-SITU RAW MATERIAL PRODUCTION AND/OR RECYCLING OF OLD COMPONENTS INTO RAW MATERIALS FOR NEW ONES THAT CAN FURTHER REDUCE IN LIFECYCLE COST FOR SPACE SYSTEMS. THE WORK OUTLINED IN THIS PROPOSAL AIMS TO DETERMINE THE NECESSARY PARAMETERS OF FUTURE PROFITABLE SPACE-BASED MANUFACTURING OPERATIONS WITHIN THE ENVIRONMENT OF THE NEW SPACE ECONOMY WITH AN EMPHASIS ON ADDITIVE MANUFACTURING TECHNOLOGIES. BUILDING ON OUR PRIOR WORK VALIDATED SYSTEM MODELS WILL BE DEVELOPED WHICH ACCOUNT FOR TECHNOLOGY DEVELOPMENT CUSTOMER DEMAND VOLUMES SUPPLIER CAPABILITIES AND THE CONSTRAINTS OF ORBITAL MECHANICS IN ORDER TO EXPLORE THE TRADE SPACE. SYSTEM SIMULATIONS WILL BE USED TO OBTAIN AND EVALUATE BREAKPOINTS AT WHICH SPACE-BASED MANUFACTURING ALLOWS FOR CHEAPER FASTER AND MORE EFFICIENT PROFITABLE SPACECRAFT SUPPLY CHAINS. RESULTS WILL BE MEASURED AGAINST BASELINE CASES IN WHICH ALL MATERIAL IS LAUNCHED FROM EARTH. THE FINDINGS OF THIS RESEARCH WILL BE DISSEMINATED THROUGH A SERIES OF CONFERENCE PROCEEDINGS AND JOURNAL ARTICLES. SPACE-BASED MANUFACTURING WILL BE A KEY ENABLER OF THE NEW SPACE ECONOMY AND IS A REQUIREMENT FOR A FUTURE EARTH-INDEPENDENT SPACE ECOSYSTEM. UNDERSTANDING THE TECHNOLOGY DEVELOPMENTS MARKET FORCES AND SYSTEM DYNAMICS OF SUCH A SYSTEM IS AN IMPORTANT STEP TOWARD THE SECOND SPACE AGE.