THE PROBLEMS OF THE ORIGIN OF LIFE AND THE ORGANIZATION OF THE BIOSPHERE ARE NOT INDEPENDENT BUT ARE TWO FACETS OF THE LARGER PROBLEM OF UNDERSTANDING THE NATURE OF LIFE IN ITS PLANETARY CONTEXT. RESEARCH IN BIOLOGY HAS ACHIEVED CONSIDERABLE INTEGRATION WITH THE BEGINNING OF THE UNIFICATION OF EVOLUTION AND DEVELOPMENT BUT RESEARCH INTO THE ORIGIN OF LIFE IS STILL POORLY CONNECTED TO THESE FIELDS AND ITS OWN INTERNAL PROJECTS ARE FRAGMENTED AND POSSESS ONLY A RUDIMENTARY CONCEPTUAL FOUNDATION. WE THEREFORE PROPOSE TO HOST AN INTENSIVE WORKSHOP TITLED RE-CONCEPTUALIZING THE ORIGIN OF LIFE TO BE HELD AT THE CARNEGIE INSTITUTION OF WASHINGTON IN WASHINGTON DC NOV. 9TH 13TH 2015. A ROSTER OF ABOUT 30 INVITED SPEAKERS AND 50 SUBMITTED POSTER PRESENTERS WILL BE BROUGHT TOGETHER FOR THIS MEETING. SINCE THE GOAL OF THE MEETING IS TO MAKE A TRANSFORMATIVE IMPACT ON THE ORIGIN OF LIFE FIELD BY ESTABLISHING NEW RESEARCH DIRECTIONS AND IDENTIFYING CORE UNANSWERED QUESTIONS ENGAGEMENT IN THIS MEETING BY EARLY-CAREER PROFESSIONALS IS ESPECIALLY SOUGHT. WE ARE THEREFORE REQUESTING FUNDS TO SUPPORT PARTICIPATION OF EARLY-CAREER SCIENTISTS WHO WILL SET THE FUTURE DIRECTION OF ORIGIN OF LIFE RESEARCH. THE MEETING WILL FOCUS ON FIVE INTEGRATIVE THEMES THAT EXPLORE THE CONCRETE AND CONCEPTUAL DIMENSIONS OF ORIGINS THE CONNECTIONS TO PLANETARY CONTEXT AND BIOLOGICAL EVOLUTION AND ECOLOGY THE ROLES OF MODELING AND COMPUTATION AND THE RELATION OF BIOLOGICAL THEORY TO FUNDAMENTAL PRINCIPLES GOVERNING ORDER IN PHYSICS CHEMISTRY MATHEMATICS AND ENGINEERING. THE FORMAT OF THE WORKSHOP IS DESIGNED TO BE OF BROAD SCOPE BUT TARGETED TO IMPACT THE CORE CONCEPTS AND UNIFYING QUESTIONS ABOUT THE ORIGIN OF LIFE AND THE ORGANIZATION OF THE BIOSPHERE.