PATTERNING BY TGF BETA IN EARLY XENOPUS EMBRYOS
$261,636R01FY2002HDNIH
Dana-Farber Cancer Institute, Boston MA
Investigators
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Abstract
DESCRIPTION: The investigator will attempt to determine how cells respond to different doses of inducers such as activin, a TGF-beta superfamily member (TGF-SM) Using a variety of readouts he plans to determine how individual cells respond to different concentrations of TGF-SMs. He also proposes to determine the effects on different processes in Xenopus development when different TGF-SM pathways are activated or blocked.
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