RNA Structure and Function Studies via Gene Construction
$327,711R01FY2002GMNIH
University Of Colorado At Boulder, Boulder CO
Investigators
Linked publications & trials
Paper 23097422Paper 16641318Paper 16373489Paper 16237127Paper 15383677Paper 14561885Paper 12762023Paper 12458080Paper 11847556Paper 11790093Paper 11401543Paper 11112541Paper 11073222Paper 10786839
Abstract
DESCRIPTION (provided by applicant): This project aims to characterize direct interactions between RNA molecules and bilayer membranes, and to manipulate these interactions for experimental purposes. As a consequence of these studies, such interactions will be sought in cells. In addition, this this project proposes to find and characterize new classes of RNA enzymes that use enzymatic cofactors as and intrinsic part of their reaction mechanisms.
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