ANTICARDIOLIPIN ANTIBODIES IN ANTIPHOSPHOLIPID SYNDROME

$251,685R01FY2002ARNIH

University Of California Los Angeles, Los Angeles CA

Investigators

Linked publications & trials

Paper 20353971 Paper 19790056 Paper 19155517 Paper 18827056 Paper 18720303 Paper 17469158 Paper 17404320 Paper 17114499 Paper 16965389 Paper 16320350 Paper 15100323 Paper 12937161 Paper 12794830 Paper 12632428 Paper 11739542 Paper 11181467 Paper 11019960

Abstract

DESCRIPTION: (Adapted from the Investigator's Abstract): Aim 1 is to generate and characterize 10 IgG monoclonal aCLs. Aim 2 is to analyze monoclonal aCLs in the in vivo fetal loss model. Aim 3 is to identify and characterize the mimetics for pathogenic aCL. Aim 4 is to do immunological and functional studies of antibodies against mimetics in APS patients. Aim 5 is to apply mimetics to study pathogenic aCL in APS patients and controls.

View original record on NIH RePORTER →