CLOTBUST

$143,375P50FY2002NSNIH

University Of Texas Hlth Sci Ctr Houston, Houston TX

Investigators

Linked publications, trials & patents

Paper 38390802 Paper 35346660 Paper 34387132 Paper 33002913 Paper 32737961 Paper 32319963 Paper 30442422 Paper 30249518 Paper 29062975 Paper 28507269 Paper 27834742 Paper 26722667 Paper 26407682 Paper 26116594 Paper 26087278 Paper 25079049 Paper 24694764 Paper 24425123 Paper 24425115 Paper 24370757 Paper 24321775 Paper 24159060 Paper 23929748 Paper 23897642 Paper 23767957 Paper 23709737 Paper 23684084 Paper 23598523 Paper 23579589 Paper 23570219 Paper 23412378 Paper 23339963 Paper 23227830 Paper 23207423 Paper 23103046 Paper 23017088 Paper 22355814 Paper 22340518 Paper 22223237 Paper 22223235 Paper 21732225 Paper 21706265 Paper 21349968 Paper 21293014 Paper 21257826 Paper 20977539 Paper 20847316 Paper 20828876 Paper 20335564 Paper 20185779 Paper 19745181 Paper 19670432 Paper 19409525 Paper 19359652 Paper 19272734 Paper 19251183 Paper 19237905 Paper 19131657 Paper 19039213 Paper 18948603 Paper 18779419 Paper 18772444 Paper 18625852 Paper 18474730 Paper 18356546 Paper 18332342 Paper 18332150 Paper 18190818 Paper 18174476 Paper 17963915 Paper 17885255 Paper 17682365 Paper 17502578 Paper 17172550 Paper 16924029 Paper 16908730 Paper 16888380 Paper 15548777 Paper 15375308 Trial NCT01123161 Trial NCT00827892 Trial NCT00268762

Abstract

DESCRIPTION (provided by the applicant): The primary specific aims for this pilot Phase II studies are: 1. To determine complete recanalization and early clinical recovery rates in patients treated with intravenous TPA and continuously monitored with an external ultrasound compared to those treated with standard TPA dose alone. 2. To determine if continuous monitoring of TPA infusion with external ultrasound is safe and will not result in higher rates of symptomatic intracerebral hemorrhage compared to controls. 3. Data generated during this Phase II trial will form the basis for a design of a properly powered multicenter Phase III trial.

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