SBIR Phase I: Synthesis of Novel Compounds by Modified RNA

Cropsolution, Inc., Morrisville NC

Investigators

Abstract

This Small Business Innovation Research (SBIR) Phase I project proposes to develop a novel method, Evolutionary Chemistry, to simultaneously generate and select from a library of small molecules, using modified RNA both as a catalyst and as an amplifiable tag for detection of binding to a target. The commercial application of this project will be to streamline the process of discovery of new compounds for therapeutic and agricultural use.