Core--Transgenic Animal Core

$0P50FY2002CANIH

University Of Michigan At Ann Arbor, Ann Arbor MI

Investigators

Linked publications & trials

Paper 28286871 Paper 27783979 Paper 26955778 Paper 26579618 Paper 26568983 Paper 26431589 Paper 26181290 Paper 26119946 Paper 26035795 Paper 25909600 Paper 25792532 Paper 25766633 Paper 25628462 Paper 25600590 Paper 25564677 Paper 25483425 Paper 25442794 Paper 24981707 Paper 24954547 Paper 24909174 Paper 24896823 Paper 24836649 Paper 24675873 Paper 24562382 Paper 24440675 Paper 24403863 Paper 24371848 Paper 24166368 Paper 24151536 Paper 24051516 Paper 23982144 Paper 23973527 Paper 23776643 Paper 23726004 Paper 23544166 Paper 23520337 Paper 23519702 Paper 23502247 Paper 23454750 Paper 23372646 Paper 23323156 Paper 23308059 Paper 23226501 Paper 23095324 Paper 23066439 Paper 23042237 Paper 23041325 Paper 23023785 Paper 23022051 Paper 22975677 Paper 22613880 Paper 22563192 Paper 22542461 Paper 22536446 Paper 22463021 Paper 22463020 Paper 22427239 Paper 22411900 Paper 22356298 Paper 22300987 Paper 22266857 Paper 22241961 Paper 22190845 Paper 22190279 Paper 22142194 Paper 22138753 Paper 22024362 Paper 21948232 Paper 21928310 Paper 21859840 Paper 21816190 Paper 21811604 Paper 21751414 Paper 21693098 Paper 21633667 Paper 21530871 Paper 21527563 Paper 21483619 Paper 21408169 Paper 21300915 Paper 21276769 Paper 21267448 Paper 21258526 Paper 21153371 Paper 21136184 Paper 21075334 Paper 20979407 Paper 20964352 Paper 20871938 Paper 20860004 Paper 20855560 Paper 20818379 Paper 20722417 Paper 20656254 Paper 20615241 Paper 20577779 Paper 20575076 Paper 20561505 Paper 20531309 Paper 20504274

Abstract

DESCRIPTION (provided by applicant): The Transgenic Animal Core will provide two core services to the projects described in this proposal: 1. Transgenic Services. The transgenic unit will provide pronuclear microinjection of DNA constructs into fertilized mouse eggs leading to the development of gene modified mouse lines expressing modified genes and gene products to facilitate imaging analysis. 2. Germline Modification Services. This unit will provide gene targeting technology services. Gene targeted mouse lines via ES cell lines will be developed, leading to homozygous knock-in constructs human genes of interest in this animal models.

View original record on NIH RePORTER →