Core--Tissue and pathology

$0P50FY2002CANIH

Dana-Farber Cancer Institute, Boston MA

Investigators

Linked publications & trials

Paper 39663641 Paper 39120256 Paper 38894678 Paper 38687617 Paper 38182874 Paper 37689063 Paper 37663929 Paper 37558833 Paper 37249585 Paper 36909640 Paper 36622276 Paper 36413141 Paper 36125519 Paper 36125434 Paper 36103646 Paper 35836303 Paper 35695870 Paper 35584006 Paper 35523889 Paper 35254710 Paper 35201849 Paper 35131873 Paper 35121110 Paper 35105671 Paper 35031563 Paper 34939926 Paper 34911936 Paper 34880124 Paper 34496240 Paper 34256096 Paper 34168052 Paper 33956343 Paper 33888356 Paper 33863813 Paper 33860950 Paper 33849963 Paper 33627383 Paper 33500320 Paper 33168599 Paper 33086052 Paper 33062306 Paper 32913135 Paper 32624279 Paper 32556091 Paper 32484436 Paper 32478682 Paper 32164144 Paper 32127465 Paper 31912798 Paper 31754047 Paper 31676563 Paper 31591549 Paper 31554818 Paper 31525487 Paper 31363002 Paper 31318977 Paper 31179538 Paper 31155658 Paper 31101725 Paper 31095304 Paper 31085648 Paper 31061129 Paper 30894499 Paper 30893145 Paper 30890759 Paper 30867220 Paper 30811282 Paper 30773341 Paper 30602500 Paper 30578319 Paper 30537509 Paper 30500466 Paper 30496346 Paper 30469014 Paper 30427533 Paper 30420441 Paper 30385733 Paper 30382943 Paper 30333152 Paper 30327313 Paper 30302603 Paper 30301696 Paper 30242839 Paper 30242112 Paper 30237027 Paper 30224544 Paper 30217568 Paper 30165429 Paper 30141208 Paper 30108097 Paper 30082473 Paper 30021909 Paper 30012673 Paper 30009541 Paper 29921690 Paper 29915914 Paper 29882250 Paper 29786791 Paper 29707790 Paper 29263420

Abstract

DESCRIPTION (provided by applicant): The Tissue and Pathology Core has two specific aims. The first specific aim is to provide a tissue and blood repository for use by SPORE investigators. Two independent tissue banks have been previously established at three of the performance institutions in this SPORE. A joint Brigham and Women's/Dana-Farber Cancer Institute Bank (BWH/DFCI Prostate Tissue Bank) and a bank at the Beth Israel Deaconess Medical Center. These tissue resources together with the DFCI Blood Component Repository will together comprise the SPORE Tissue and Blood Repositories. The tissue and Pathology Core will collect, freeze, and store a) fresh samples of prostate cancer and paired non-tumor prostate tissue; b) blood and blood components (plasma, peripheral blood mononuclear cells from patients with prostate cancer). The Tissue and Pathology Core will also identify, collect and provide investigators with samples of fixed tissues from biopsy and prostatectomy specimens of patients who are consented, to allow analysis of these tissues in combination with associated clinical data. The second major specific aim of this Core is to provide research pathology services to SPORE investigators, including histology, immunohistochemistry, in situ hybridization, computer-assisted image analysis, laser capture microdissection, and the generation of and access to tissue microarrays. The Tissue and Pathology Core will create a seamless informatics link between the extensive existing tissue resources among the Dana Farber/Harvard Cancer Center (DF/HCC) hospitals. Thus, one of the major goals of this core facility is to create a tissue and blood resource, linked to clinical outcome data, behind a secure data management system that will be available to DF/HCC SPORE investigators as well as SPORE investigators at other institutions. In this regard there will be close collaboration between the Tissue and Pathology Core and the Biostatistics Core. The Biostatistics core will be responsible for assisting in the data analysis and data auditing.

View original record on NIH RePORTER →