Applications of Bismuth Compounds in Organic Synthesis

Illinois Wesleyan University, Bloomington IL

Investigators

Abstract

The focus of this research involves the development of diverse methodology for use of bismuth compounds as relatively nontoxic, low cost reagents that are insensitive to small amounts of air and moisture. Dehydration of oximes, allylations, epoxides-olefin cyclizations and the synthesis of resorcinarenes will all be carried out. Undergraduate co-workers will have an important role in this research effort that stresses the development of environmentally friendly chemistry. With this Research in Undergraduate Institutions (RUI) award, the Organic and Macromolecular Chemistry Program is supporting the research of Dr. Ram S. Mohan in the Department of Chemistry at Illinois Wesleyan. Professor Mohan will focus his research efforts on developing methodology for the use of bismuth reagents as catalysts in organic synthesis. There is potential for broader impact of the work in the use of green chemistry in the pharmaceutical industry and the project presents an excellent venue for the training of undergraduate students.