MRI: Acquisition of a Liquid Chromatograph-Mass Spectrometer System for Chemistry and Biology

San Diego State University Foundation, San Diego CA

Investigators

Abstract

With this award from the Major Research Instrumentation (MRI) Program, the Department of Chemistry at San Diego State University will acquire a liquid chromatograph with mass spectrometric detection (LC-MS). This equipment will enhance research in the following areas: a) the development of methods for analyzing air- and/or water-sensitive materials; and studies of b) organometallic complexes and polymers containing two or more metals; c) organometallic complexes of proteins and peptides; d) protein and peptide interactions with DNA; and e) supramolecular interactions of electrogenerated radical anions with hydrogen-bond donors . Liquid chromatography with mass spectrometric detection (LC-MS) is an extremely powerful technique used for the separation and analysis of complex mixtures. This instrument will have an impact in the areas of chemistry, materials science and biochemistry.