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SELF ASSEMBLED POLYMER THIN FILMS BOUND TO SOLID SURFACES: TISSUE ENGINEERING

$0P41FY2002RRNIH

University Of Washington, Seattle WA

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Abstract

The goal of this project is to design a family of new polymeric materials which spontaneously assemble on solid surfaces, forming bound polymer monolayers. The materials will be used as surface modification agents, presenting well-defined surfaces for applications in cell and tissue engineering, lubrication, adhesion, and corrosion. Polymer architectures comprising three specific elements which promote self-assembly are being used 1) specific anchor groups known to chemisorb to metal and oxide surfaces, 2) a flexible polymer backbone which links multiple side chains, and 3) a set of functional groups or side chains which impart a functional character to the polymer film.

View original record on NIH RePORTER →