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STRUCTURE DETERMINATION OF PEPTIDYLGLYCINE HYDROXYLATING MONOOXGENASE

$143,176P41FY2002RRNIH

Stanford University, Stanford CA

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Linked publications & trials

Abstract

Structural studies of PHM will have a great impact in several areas of research. They will provide a structural model to test proposed reaction mechanisms, provide pharmacological information aiding the synthesis of bioactive hormones, provide the first structure of a novel enzyme class and perhaps a novel folding motif, provide a model to study the structure and reaction mechanism of DbM through homology and provide a structural explanation of the observed substrate specificity.

View original record on NIH RePORTER →